Current Status of Natural Products from Plants as Anti-herpes Simplex Virus 1 Agents

被引：3

作者：

Yangfei XIANG Ying PEI and Yifei WANG Biomedicine Research Development Center Jinan University Guangzhou China ^{[510630
]}

机构：

来源：

Virologica Sinica | 2008年 / 05期

关键词：

D O I：

暂无

中图分类号：

R284 [中药化学];

学科分类号：

100804 [中药化学];

摘要：

Nucleoside analogues have been the mainstay of clinical treatment of herpes simplex virus 1 (HSV-1) infections since their development. However, the emergence of drug resistant strains has underlined the urgency of the discovery of novel anti-HSV-1 drugs. Natural products, which provided many novel drug leads, are known to be an important source of anti-HSV-1 agents. Herein, we present an overview of natural products with anti-HSV-1 activities isolated from a variety of plants reported in recent years. Several different compounds, mainly belonging to the three groups of polysaccharides, polyphenols and terpenes, showed antiviral effects against HSV-1, indicating their potential to be promising anti-HSV-1 agents.

引用

页码：305 / 314

页数：10

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