In vitro antiviral effect of meroditerpenes isolated from the Brazilian seaweed Stypopodium zonale (Dictyotales)

被引：33

作者：

Soares, Angelica Ribeiro

Abrantes, Juliana Lourenco

Lopes Souza, Thiago Moreno

Leite Fontes, Carlos Frederico

Pereira, Renato Crespo

de Palmer Paixao Frugulhetti, Izabel Christina

Teixeira, Valeria Laneuville ^{[1
]}

机构：

[1] Univ Fed Fluminense, Dept Biol Marinha, Inst Biol, Niteroi, RJ, Brazil

[2] Univ Fed Fluminense, Programa Posgrad Quim Organ, Inst Quim, Niteroi, RJ, Brazil

[3] Univ Fed Fluminense, Programa Posgrad Neuroimunol, Inst Biol, Niteroi, RJ, Brazil

[4] Univ Fed Rio de Janeiro, Programa Posgrad Quim Biol, Inst Bioquim Med, Rio De Janeiro, Brazil

[5] Univ Fed Fluminense, Dept Biol Celular & Mol, Inst Biol, Niteroi, RJ, Brazil

来源：

PLANTA MEDICA | 2007年 / 73卷 / 11期

关键词：

D O I：

10.1055/s-2007-981589

中图分类号：

Q94 [植物学];

学科分类号：

071001 [植物学];

摘要：

The meroditerpenoids atomaric acid (1), epitaondiol (2) and the peroxylactone of 5'a-desmethyl-5'-acetylatomaric acid (3) were isolated from the Brazilian brown alga Stypopodium zonale collected in two localities (Buzios and Marataizes, RJ and ES States). These compounds showed strong anti-HSV-1 activity in vitro but neither of them inhibited the transcriptase reverse enzyme of HIV-1.

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页码：1221 / 1224

页数：4

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