急性肺损伤和急性呼吸窘迫综合征发病机制的研究现状与展望

被引：13

作者：

徐思娟

彭再梅

机构：

[1] 中南大学湘雅二医院急诊科

来源：

中华急诊医学杂志 | 2014年 / 23卷 / 10期

基金：

湖南省自然科学基金;

关键词：

D O I：

暂无

中图分类号：

R563.8 [呼吸衰竭];

学科分类号：

100201 [内科学];

摘要：

<正>急性肺损伤(acute lung jnjury,ALI)和急性呼吸窘迫综合征(acute respiratory distress syndrome,ARDS)是一种急性弥漫性肺部炎症性肺损伤,伴随肺泡-毛细血管膜通透性增加所致的肺水肿,临床主要特征为低氧合、低肺顺应性、生理死腔增加及X线双肺斑片影。此定义基于近年来的研究,且认为ALI与ARDS的病因及发病机制均相同,仅仅是氧合受损程度及临床表现轻重不一,而且此二者是同一综合征的病情差别的表现,所以2011年欧洲危重症协

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