植物萜类生物合成中的后修饰酶

被引:66
作者
李军玲 [1 ,2 ]
罗晓东 [1 ]
赵沛基 [1 ]
曾英 [1 ]
机构
[1] 中国科学院昆明植物研究所植物化学与西部植物资源持续利用国家重点实验室
[2] 中国科学院研究生院
关键词
萜类合酶; 后修饰; P450单氧酶; 双键还原酶; 酰基转移酶; 糖基转移酶;
D O I
暂无
中图分类号
R284.1 [化学分析与鉴定];
学科分类号
100804 [中药化学];
摘要
萜类化合物由于其结构类型丰富多样而被称为"terpenome"。除了参与植物生长发育、环境应答等生理过程,萜类化合物还应用于医药、有机化工等领域。萜类的生物合成大致可分为前体形成、骨架构建以及后修饰三部分,基本骨架通常由萜类合酶催化形成,进一步在后修饰酶的作用下产生数以万计的萜类化合物。结合我们对香茶菜二萜生物合成的初步研究结果,本文主要针对近年来植物萜类生物合成中的一些有代表性的后修饰酶包括P450单氧酶、双键还原酶、酰基转移酶和糖基转移酶,进行研究现状分析与展望。
引用
收藏
页码:461 / 468
页数:8
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