胎盘生长因子与妊娠关系的研究进展

被引：7

作者：

郭芳芳

杨洁霞

机构：

[1] 广东省妇幼保健院产前诊断与遗传病诊疗中心

来源：

中国妇幼保健 | 2014年 / 29卷 / 36期

关键词：

PLGF; 异位妊娠; 宫外孕; 妊娠病; 胎盘; 先兆子痫; 生长因子;

D O I：

暂无

中图分类号：

R714 [产科学];

学科分类号：

100211 ;

摘要：

<正>胎盘生长因子(PLGF)是近年来国内外学者研究非常热门的一个肝素结合酸性蛋白,属于血管内皮生长因子家族(VEGF)。由于其显著的血管生成特性,使得该因子与妊娠、炎症反应、心血管疾病、肿瘤等都有着密切的关系。PLGF丰富表达于胎盘,与血管新生、内皮细胞和滋养细胞功能相关,对胎盘形成和胎儿发育有着重要作用,其表达异常与不良妊娠结局以及妊娠相关并发症密切相关,故对其深入的研究对于妊娠相关疾病的临床指导及辅助诊断有着重要

引用

页码：6173 / 6175

页数：3

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