木脂素类化合物生物活性研究进展

被引:66
作者
张国良
李娜
林黎琳
王明伟
机构
[1] 国家新药筛选中心
关键词
木脂素; 生物活性; 芳基萘; 二苄基丁内酯;
D O I
暂无
中图分类号
R284 [中药化学];
学科分类号
100804 [中药化学];
摘要
木脂素类化合物是自然界中普遍存在的一类物质,具有抗肿瘤,抗炎,抗病毒,保肝及抑制血小板活化因子(PAF)等生理功能。随着植化分离手段和结构鉴定方法的提高,先进的药物高通量筛选技术之广泛应用,越来越多的该类化合物和相关生物活性被相继报道。作者从芳基萘,二苄基丁内酯,四氢呋喃,二苄基丁烷,联苯环辛烯,新木脂素等6个方面对这类化合物的生物活性进行总结,旨在促进对木脂素类化合物的研究和开发。
引用
收藏
页码:2089 / 2094
页数:6
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