Phytochemistry and Pharmacology of Sesquiterpenoids from Atractylodes DC. Genus Rhizomes

被引:6
作者
Qu, Zhengyi [1 ,2 ]
Liu, Hongqun [3 ]
Zhang, Zhenghai [4 ]
Zheng, Peihe [4 ]
Zhao, Shuting [1 ,2 ]
Hou, Wei [1 ,2 ]
机构
[1] Chinese Acad Agr Sci, Inst Special Wild Econ Anim & Plants, Changchun 130112, Peoples R China
[2] Jilin Prov Key Lab Tradit Chinese Med Mat Cultivat, Changchun 130112, Peoples R China
[3] Changchun Sci Tech Univ, Med Sch, Changchun 130600, Peoples R China
[4] Jilin Agr Sci & Technol Univ, Tradit Chinese Med Sch, Jilin, Peoples R China
关键词
Atractylodes DC. rhizomes; sesquiterpenes; eudesmane-type; phytochemistry; biosynthetic pathways; pharmacology; EREMOPHILANE-TYPE SESQUITERPENOIDS; ATRACTYLENOLIDE-I; ESSENTIAL OIL; INFLAMMATORY RESPONSES; MACROCEPHALA; LANCEA; CONSTITUENTS; GLYCOSIDES; APOPTOSIS; PATHWAY;
D O I
10.3390/molecules29061379
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
070307 [化学生物学]; 071010 [生物化学与分子生物学];
摘要
The rhizomes of the genus Atractylodes DC. consist of various bioactive components, including sesquiterpenes, which have attracted a great deal of research interest in recent years. In the present study, we reviewed the previously published literatures prior to November 2023 on the chemical structures, biosynthetic pathways, and pharmacological activities of the sesquiterpenoids from this genus via online databases such as Web of Science, Google Scholar, and ScienceDirect. Phytochemical studies have led to the identification of more than 160 sesquiterpenes, notably eudesmane-type sesquiterpenes. Many pharmacological activities have been demonstrated, particularly anticancer, anti-inflammatory, and antibacterial and antiviral activities. This review presents updated, comprehensive and categorized information on the phytochemistry and pharmacology of sesquiterpenes in Atractylodes DC., with the aim of offering guidance for the future exploitation and utilization of active ingredients in this genus.
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页数:42
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