Enantioselective C-H amination using cationic ruthenium(II)-pybox catalysts

被引：242

作者：

Milczek, Erika ^{[1
]}

Boudet, Nadege ^{[1
]}

Blakey, Simon ^{[1
]}

机构：

[1] Emory Univ, Dept Chem, Atlanta, GA 30322 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2008年 / 47卷 / 36期

关键词：

amination; asymmetric catalysis; C-H activation; ruthenium;

D O I：

10.1002/anie.200801445

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The whole "pybox" and dice: Highly enantioselective amination reactions of both allylic and benzylic C-H bonds are catalyzed by cationic ruthenium(II)-pybox complexes (see structure). A novel mode of stereocontrol, which is induced by the versatile pybox ligand, is proposed to account for the excellent enantioselectivity in these reactions. Boc = tert-butoxycarbonyl, pybox = pyridine bisoxazoline. (Chemical Equation Presented) © 2008 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：6825 / 6828

页数：4

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