Stereoselective palladium(0)-mediated synthesis of unsaturated 1,4-disaccharides

被引：15

作者：

Frappa, I

Kryczka, B

Lhoste, P

Porwanski, S

Sinou, D

机构：

[1] UNIV LYON 1,CPE LYON,CNRS,LAB SYNTH ASYMETR,F-69622 VILLEURBANNE,FRANCE

[2] UNIV LODZ,DEPT ORGAN & APPL CHEM,PL-90136 LODZ,POLAND

来源：

JOURNAL OF CARBOHYDRATE CHEMISTRY | 1997年 / 16卷 / 06期

关键词：

D O I：

10.1080/07328309708006546

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Unsaturated 1,4-disaccharides are obtained in quite good yields by alkylation of ethyl alpha-O-Delta(2)-glycosides, having a leaving group at C-4, with various 1-hydroxycarbohydrates in the presence of a catalytic amount of palladium(0). The reaction is regio- and stereospecific for alpha-erythro enosides 3 and 5, and only stereospecific in the case of the beta-threo enoside 7, alkylation occurring at C-4 and C-2 in this case.

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页码：891 / 910

页数：20

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