Cobalt-catalyzed [2+2] cycloaddition

被引：69

作者：

Treutwein, Jonas ^{[1
]}

Hilt, Gerhard ^{[1
]}

机构：

[1] Univ Marburg, Fachbereich Chem, D-35043 Marburg, Germany

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2008年 / 47卷 / 36期

关键词：

alkenes; alkynes; cobalt; cycloaddition;

D O I：

10.1002/anie.200801778

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Chemical Equation Presented) Three's a charm, but four's not half bad either: A simple cobalt-diphosphine complex facilitates the synthesis of cyclobutene derivatives through the chemoselective transformation of strained five-membered unsaturated rings with internal alkynes (see scheme). This atom-efficient, intermolecular reaction generates polycyclic products in excellent yields and with excellent exo selectivity. dppp=1,3- bis(diphenylphosphanyl)propane. © 2008 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：6811 / 6813

页数：3

共 31 条

[21] On inventing reactions for atom economy [J].

Trost, BM .

ACCOUNTS OF CHEMICAL RESEARCH, 2002, 35 (09) :695-705

[22]

Trost BM, 2002, CHEM-EUR J, V8, P2341, DOI 10.1002/1521-3765(20020517)8:10<2341::AID-CHEM2341>3.0.CO

[23]

2-A

[24] RUTHENIUM-CATALYZED ADDITION OF ALLYL ALCOHOLS AND ACETYLENES - A SIMPLE SYNTHESIS OF GAMMA,DELTA-UNSATURATED KETONES [J].

TROST, BM ;

MARTINEZ, JA ;

KULAWIEC, RJ ;

INDOLESE, AF .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1993, 115 (22) :10402-10403

[25] A regioselective Ru-catalyzed alkene-alkyne coupling [J].

Trost, BM ;

Machacek, M ;

Schnaderbeck, MJ .

ORGANIC LETTERS, 2000, 2 (12) :1761-1764

[26] Synthesis and unusual [2+2] cycloaddition reactions of 1-trifluoroacetyl-2-haloacetylenes [J].

Tsvetkov, NP ;

Koldobskii, AB ;

Kalinin, VN .

DOKLADY CHEMISTRY, 2005, 404 (1-3) :174-177

[27] Asymmetric induction in ruthenium-catalyzed [2+2] cycloadditions between bicyclic alkenes and a chiral acetylenic acyl sultam [J].

Villeneuve, K ;

Tam, W .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2004, 43 (05) :610-613

[28] Ruthenium-catalyzed [2+2] cycloadditions of bicyclic alkenes and ynamides [J].

Villeneuve, K ;

Riddell, N ;

Tam, W .

TETRAHEDRON, 2006, 62 (16) :3823-3836

[29] Diastereoselective ruthenium-catalyzed [2+2] cycloadditions between bicyclic alkenes and a chiral propargylic alcohol and its derivatives [J].

Villeneuve, K ;

Jordan, RW ;

Tam, W .

SYNLETT, 2003, (14) :2123-2128

[30]

VILLENEUVE K, 2004, ANGEW CHEM, V116, P620

← 1 2 3 4 →