Angiogenesis in the mouse retina: A model system for experimental manipulation

被引：65

作者：

Uemura, AK ^{[1
]}

Kusuhara, S ^{[1
]}

Katsuta, H ^{[1
]}

Nishikawa, S ^{[1
]}

机构：

[1] RIKEN, Ctr Dev Biol, Lab Stem Cell Biol, Chuo Ku, Kobe, Hyogo 6500047, Japan

来源：

EXPERIMENTAL CELL RESEARCH | 2006年 / 312卷 / 05期

关键词：

angiogenesis; retina; manipulation;

D O I：

10.1016/j.yexcr.2005.10.030

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The vascular system of the mouse retina provides a useful model for analyzing the molecular and cellular mechanisms regulating angiogenesis because (1) hierarchical vascular networks are newly formed only after birth, (2) the cellular components involved in angiogenesis are well characterized, and (3) all the processes are accessible for monitoring and manipulation. In this article, we present an overview of our current understanding of the process of retinal angiogenesis and describe a number of methodologies applicable to experimental manipulation of the retinal vascular system. (c) 2005 Elsevier Inc. All rights reserved.

引用

页码：676 / 683

页数：8