Histone acetylation in signal transduction by growth regulatory signals

被引：22

作者：

Magnaghi-Jaulin, L ^{[1
]}

Ait-Si-Ali, S ^{[1
]}

Harel-Bellan, A ^{[1
]}

机构：

[1] IRC, CNRS, UPR 9079, F-94800 Villejuif, France

来源：

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY | 1999年 / 10卷 / 02期

关键词：

CBP; chromatin; E2F; histone acetylation; Rb;

D O I：

10.1006/scdb.1999.0301

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Cell fate is determined by extracellular signals which are transmitted to the nucleus and result in the transcriptional regulation of specific subsets of genes. Transcriptional regulation has been recently linked to enzymatic activities which are able to acetylate or deacetylate core histone tails. A number of transcriptional co-regulators are histone acetyltransferases or histone deacetylases. Here, we discuss the involvement of these enzymes in critical steps of cell proliferation or cell differentiation control.

引用

页码：197 / 203

页数：7

共 107 条

[1] CREB-binding protein in androgen receptor-mediated signaling
Aarnisalo, P
Palvimo, JJ
Jänne, OA
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (05) : 2122 - 2127
[2] AITSIALI S, 1998, IN PRESS NATURE
[3] Role for N-CoR and histone deacetylase in Sin3-mediated transcriptional repression
Alland, L
Muhle, R
Hou, H
Potes, J
Chin, L
SchreiberAgus, N
DePinho, RA
[J]. NATURE, 1997, 387 (6628) : 49 - 55
[4] MYC-MAX-MAD - A TRANSCRIPTION FACTOR NETWORK CONTROLLING CELL-CYCLE PROGRESSION, DIFFERENTIATION AND DEATH
AMATI, B
LAND, H
[J]. CURRENT OPINION IN GENETICS & DEVELOPMENT, 1994, 4 (01) : 102 - 108
[5] E1A-ASSOCIATED P300 AND CREB-ASSOCIATED CBP BELONG TO A CONSERVED FAMILY OF COACTIVATORS
ARANY, Z
SELLERS, WR
LIVINGSTON, DM
ECKNER, R
[J]. CELL, 1994, 77 (06) : 799 - 800
[6] MAD-MAX TRANSCRIPTIONAL REPRESSION IS MEDIATED BY TERNARY COMPLEX-FORMATION WITH MAMMALIAN HOMOLOGS OF YEAST REPRESSOR SIN3
AYER, DE
LAWRENCE, QA
EISENMAN, RN
[J]. CELL, 1995, 80 (05) : 767 - 776
[7] BLACKWOOD EM, 1991, COLD SPRING HARB SYM, V56, P109
[8] The histone acetylase PCAF is a nuclear receptor coactivator
Blanco, JCG
Minucci, S
Lu, JM
Yang, XJ
Walker, KK
Chen, HW
Evans, RM
Nakatani, Y
Ozato, K
[J]. GENES & DEVELOPMENT, 1998, 12 (11) : 1638 - 1651
[9] Control of cell proliferation by Myc
Bouchard, C
Staller, P
Eilers, M
[J]. TRENDS IN CELL BIOLOGY, 1998, 8 (05) : 202 - 206
[10] STIMULATION AND INHIBITION OF GROWTH BY EGF IN DIFFERENT A431 CELL CLONES IS ACCOMPANIED BY THE RAPID INDUCTION OF C-FOS AND C-MYC PROTO-ONCOGENES
BRAVO, R
BURCKHARDT, J
CURRAN, T
MULLER, R
[J]. EMBO JOURNAL, 1985, 4 (05) : 1193 - 1197

← 1 2 3 4 5 6 7 8 9 10 →