A multisubstrate adduct inhibitor of AICAR transformylase

被引：13

作者：

Wall, M ^{[1
]}

Shim, JH ^{[1
]}

Benkovic, SJ ^{[1
]}

机构：

[1] Penn State Univ, Dept Chem, Wartik Lab 414, University Pk, PA 16802 USA

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1999年 / 42卷 / 18期

关键词：

D O I：

10.1021/jm990323+

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：3421 / 3424

页数：4

共 18 条

[1] RATIONAL DESIGN OF ENZYME-INHIBITORS - MULTISUBSTRATE ANALOG INHIBITORS [J].

BROOM, AD .

JOURNAL OF MEDICINAL CHEMISTRY, 1989, 32 (01) :2-7

[2] MICRODETERMINATION OF PHOSPHORUS [J].

CHEN, PS ;

TORIBARA, TY ;

WARNER, H .

ANALYTICAL CHEMISTRY, 1956, 28 (11) :1756-1758

[3] SYNTHESIS AND BIOLOGICAL EVALUATION OF 8-DEAZAHOMOFOLIC ACID AND ITS TETRAHYDRO DERIVATIVE [J].

DEGRAW, JI ;

COLWELL, WT ;

BROWN, VH ;

SATO, M ;

KISLIUK, RL ;

GAUMONT, Y ;

THORNDIKE, J ;

SIROTNAK, FM .

JOURNAL OF MEDICINAL CHEMISTRY, 1988, 31 (01) :150-153

[4] THE PURINE PATH TO CHEMOTHERAPY [J].

ELION, GB .

SCIENCE, 1989, 244 (4900) :41-47

[5] A MULTISUBSTRATE ADDUCT INHIBITOR OF A PURINE BIOSYNTHETIC ENZYME WITH A PICOMOLAR DISSOCIATION-CONSTANT [J].

INGLESE, J ;

BLATCHLY, RA ;

BENKOVIC, SJ .

JOURNAL OF MEDICINAL CHEMISTRY, 1989, 32 (05) :937-940

[6] MULTISUBSTRATE ADDUCT INHIBITORS OF GLYCINAMIDE RIBONUCLEOTIDE TRANSFORMYLASE - SYNTHETIC AND ENZYME-ASSEMBLED [J].

INGLESE, J ;

BENKOVIC, SJ .

TETRAHEDRON, 1991, 47 (14-15) :2351-2364

[7] SYNTHESIS AND ANTI-MICROBIAL TESTING OF 2-AMINO-6-HYDROXYMETHYL-4-(3H)PYRIDO[3,2-D]PYRIMIDINONE [J].

KELLEY, JL ;

MCLEAN, EW .

JOURNAL OF HETEROCYCLIC CHEMISTRY, 1981, 18 (04) :671-673

[8] NUCLEOSIDES AND NUCLEOTIDES .96. SYNTHESIS AND ANTITUMOR-ACTIVITY OF 5-ETHYNYL-1-BETA-D-RIBOFURANOSYLIMIDAZOLE-4-CARBOXAMIDE (EICAR) AND ITS DERIVATIVES [J].

MINAKAWA, N ;

TAKEDA, T ;

SASAKI, T ;

MATSUDA, A ;

UEDA, T .

JOURNAL OF MEDICINAL CHEMISTRY, 1991, 34 (02) :778-786

[9] Nucleosides and nucleotides .138. Synthesis of 3-halo-3-deazainosines: Conformational lock with the halogen at the 3-position of the 3-deazainosine in anti-conformation [J].

Minakawa, N ;

Kojima, N ;

Matsuda, A .

HETEROCYCLES, 1996, 42 (01) :149-154

[10]

MUELLER WT, 1981, BIOCHEMISTRY-US, V20, P344

← 1 2 →