Polyunsaturated monoglycerides and a pregnadiene in defensive glands of the water beetle Agabus affinis

被引：10

作者：

Schaaf, O ^{[1
]}

Dettner, K ^{[1
]}

机构：

[1] Univ Bayreuth, Dept Anim Ecol 2, D-95440 Bayreuth, Germany

来源：

LIPIDS | 2000年 / 35卷 / 05期

关键词：

D O I：

10.1007/s11745-000-554-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In addition to the C-21 steroid 15 alpha-hydroxy-pregna-4, 6-dien-3,20-dione, four 1- or 2-acylated polyunsaturated monoglycerides, 1- or 2-(cis-5,8,11,14-eicosatetraenoyl)- glycerol and 1- or 2-(cis-5,8,11,14,17-eicosapentaenoyl)glycerol were identified as constituents of the prothoracic defensive gland secretion of the dytiscid beetle Agabus affinis by gas chromatography-mass spectrometry of trimethylsilylated gland extracts. In a feeding assay with minnows, synthetic samples of the two 2-acylated monoglycerides showed only a weak activity as a feeding deterrent. For that reason, other possible functions of the monoglycerides are discussed, such as roles as emulsifiers of cannabimimetics.

引用

页码：543 / 550

页数：8

共 33 条

[21]

SCHILDKNECHT H, 1977, PONT ACAD SCI SCRIPT, V41, P59

[22]

Schildknecht H., 1976, ANGEW CHEM, V88, P235

[23]

SCHILDKNECHT H, 1970, EXC MED INT C SER, V219, P158

[24]

Schildknecht H, 1968, NACHR CHEM TECH, V16, P311

[25]

Scrimshaw S., 1987, P240

[26] Correlations between the chemical structure and the pharmacological actions of the steroids [J].

Selye, H .

ENDOCRINOLOGY, 1942, 30 (03) :437-453

[27] Inhibition by 2-arachidonoylglycerol, a novel type of possible neuromodulator, of the depolarization-induced increase in intracellular free calcium in neuroblastoma x glioma hybrid NG108-15 cells [J].

Sugiura, T ;

Kodaka, T ;

Kondo, S ;

Tonegawa, T ;

Nakane, S ;

Kishimoto, S ;

Yamashita, A ;

Waku, K .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1997, 233 (01) :207-210

[28] 2-arachidonoylglycerol, a putative endogenous cannabinoid receptor ligand, induces rapid, transient elevation of intracellular free Ca2+ in neuroblastoma X glioma hybrid NG108-15 cells [J].

Sugiura, T ;

Kodaka, T ;

Kondo, S ;

Tonegawa, T ;

Nakane, S ;

Kishimoto, S ;

Yamashita, A ;

Waku, K .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1996, 229 (01) :58-64

[29] Detection of an endogenous cannabimimetic molecule, 2-arachidonoylglycerol, and cannabinoid CB1 receptor mRNA in human vascular cells: Is 2-arachidonoylglycerol a possible vasomodulator? [J].

Sugiura, T ;

Kodaka, T ;

Nakane, S ;

Kishimoto, S ;

Kondo, S ;

Waku, K .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1998, 243 (03) :838-843

[30]

UEDA I, 1994, ANESTH ANALG, V78, P718

← 1 2 3 4 →