Pulmonary MR angiography with ultrasmall superparamagnetic iron oxide particles as a blood pool agent and a navigator echo for respiratory gating:: Pilot study

In nine healthy adult volunteers, pulmonary magnetic resonance angiography was performed with the blood pool agent NC100150 Injection combined with respiratory gating with a navigator echo. With increasing doses of the contrast agent, higher signal intensities and vessel branch order visualization were achieved. No motion artifacts I were seen. The blood pool agent NC100150 Injection in combination with respiratory navigator gating permitted acquisition of high-quality MR angiograms of the pulmonary vasculature during continuous breathing.