Resolution of delta-lactams provides access to nonracemic benzoquinolinones: The synthesis of LY300502 and LY300503

被引：4

作者：

Astleford, BA ^{[1
]}

Audia, JE ^{[1
]}

Deeter, J ^{[1
]}

Heath, PC ^{[1
]}

Janisse, SK ^{[1
]}

Kress, TJ ^{[1
]}

Wepsiec, JP ^{[1
]}

Weigel, LO ^{[1
]}

机构：

[1] ELI LILLY & CO,LILLY RES LABS,CHEM PROC RES & DEV,INDIANAPOLIS,IN 46285

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1996年 / 61卷 / 13期

关键词：

D O I：

10.1021/jo9601425

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[No abstract available]

引用

页码：4450 / 4454

页数：5

共 36 条

[11] A MILD 2-STEP METHOD FOR THE HYDROLYSIS METHANOLYSIS OF SECONDARY AMIDES AND LACTAMS
FLYNN, DL
ZELLE, RE
GRIECO, PA
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1983, 48 (14) : 2424 - 2426
[12] ENZYMATIC FORMATION OF LACTAMS IN ORGANIC-SOLVENTS
GUTMAN, AL
MEYER, E
YUE, X
ABELL, C
[J]. TETRAHEDRON LETTERS, 1992, 33 (27) : 3943 - 3946
[13] LY191704 - A SELECTIVE, NONSTEROIDAL INHIBITOR OF HUMAN STEROID 5-ALPHA-REDUCTASE TYPE-1
HIRSCH, KS
JONES, CD
AUDIA, JE
ANDERSSON, S
MCQUAID, L
STAMM, NB
NEUBAUER, BL
PENNINGTON, P
TOOMEY, RE
RUSSELL, DW
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (11) : 5277 - 5281
[14] HIRSCH KS, 1992, Patent No. 531026
[15] STEROIDAL A-RING ARYL CARBOXYLIC-ACIDS - A NEW CLASS OF STEROID 5-ALPHA-REDUCTASE INHIBITORS
HOLT, DA
LEVY, MA
LADD, DL
OH, HJ
ERB, JM
HEASLIP, JI
BRANDT, M
METCALF, BW
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1990, 33 (03) : 937 - 942
[16] NONSTEROIDAL INHIBITORS OF HUMAN TYPE-I STEROID 5-ALPHA-REDUCTASE
JONES, CD
AUDIA, JE
LAWHORN, DE
MCQUAID, LA
NEUBAUER, BL
PIKE, AJ
PENNINGTON, PA
STAMM, NB
TOOMEY, RE
HIRSCH, KS
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1993, 36 (03) : 421 - 423
[17] KEARNS MA, UNPUB
[18] KRESS TJ, UNPUB
[19] THE SYNTHESIS OF (-)-4-METHYL-8-CHLORO-TRANS-1,2,3,4,4A,5,6,10B-OCTAHYDROBENZO-[F]-QUINOLIN-3-ONE-[3-C-14] (LY300502-C-14]) VIA A CIRCUITOUS ROUTE
KUO, FJ
WHEELER, WJ
[J]. JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, 1994, 34 (10) : 915 - 920
[20] A 3-D MODEL FOR 5-HT1A-RECEPTOR AGONISTS BASED ON STEREOSELECTIVE METHYL-SUBSTITUTED AND CONFORMATIONALLY RESTRICTED ANALOGS OF 8-HYDROXY-2-(DIPROPYLAMINO)TETRALIN
MELLIN, C
VALLGARDA, J
NELSON, DL
BJORK, L
YU, H
ANDEN, NE
CSOREGH, I
ARVIDSSON, LE
HACKSELL, U
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1991, 34 (02) : 497 - 510

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