Systemic lupus erythematosus induced by interferon ß1 therapy in a patient with multiple sclerosis

被引：12

作者：

Bahri, Dalila Mrabet ^{[1
]}

Khiari, Hela ^{[2
]}

Essouri, Asma ^{[2
]}

Laadhar, Lilia ^{[3
]}

Zaraa, Ines ^{[4
]}

Mrabet, Amel ^{[2
]}

Meddeb, Nihel ^{[1
]}

Sellami, Slaheddine ^{[1
]}

机构：

[1] La Rabta Hosp, Dept Rheumatol, Tunis 1007, Tunisia

[2] Charles Nicolle Hosp, Dept Neurol, Tunis 1007, Tunisia

[3] La Rabta Hosp, Dept Immunol, Tunis 1007, Tunisia

[4] La Rabta Hosp, Dept Dermatol, Tunis 1007, Tunisia

来源：

FUNDAMENTAL & CLINICAL PHARMACOLOGY | 2012年 / 26卷 / 02期

关键词：

drug-induced lupus erythematosus; interferon ss-1a; multiple sclerosis; BETA;

D O I：

10.1111/j.1472-8206.2011.00929.x

中图分类号：

R9 [药学];

学科分类号：

100702 [药剂学];

摘要：

Drug-induced lupus erythematosus is defined as a lupus-like syndrome temporally related to a drug exposure. We report a 34-year-old woman with multiple sclerosis who developed, while being treated with interferon beta-1a, myalgia and associated with wrist synovitis. Clinical and immunologic investigations were in favor of systemic lupus erythematosus. Interferon therapy was maintained. Under corticosteroids and antipaludeen treatment, the patient did not develop any other lupic manifestations.

引用

页码：210 / 211

页数：2

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