Recent Developments on the Trifluoromethylation of (Hetero)Arenes

被引：338

作者：

Wu, Xiao-Feng ^{[1
,2
]}

Neumann, Helfried ^{[2
]}

Beller, Matthias ^{[2
]}

机构：

[1] Zhejiang Sci Tech Univ, Dept Chem, Hangzhou 310018, Zhejiang, Peoples R China

[2] Leibniz Inst Katalyse eV, D-18059 Rostock, Germany

来源：

CHEMISTRY-AN ASIAN JOURNAL | 2012年 / 7卷 / 08期

关键词：

arenes; copper; homogeneous catalysis; palladium; trifluoromethylation; COPPER-CATALYZED TRIFLUOROMETHYLATION; FORMING REDUCTIVE ELIMINATION; OXIDATIVE TRIFLUOROMETHYLATION; MEDIATED TRIFLUOROMETHYLATION; AROMATIC-COMPOUNDS; NUCLEOPHILIC TRIFLUOROMETHYLATION; ASYMMETRIC FLUORINATION; CARBONYL-COMPOUNDS; CONVENIENT METHOD; ORGANIC HALIDES;

D O I：

10.1002/asia.201200211

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Aryl-CF3 as an extremely important family of fluorinated organic compounds holds wide applications in pharmaceuticals, agrochemicals, and advanced materials. Traditionally, such trifluoromethylated compounds have been synthesized from the corresponding aryl trichlorides via Cl exchange reactions (Scheme 1). This Focus review gives an overview over the recent development of trifluoromethylation of (hetero)arenes.

引用

页码：1744 / 1754

页数：11

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