Screening for crystalline salts via mechanochemistry

被引：124

作者：

Trask, AV

Haynes, DA

Motherwell, WDS

Jones, W

机构：

[1] Univ Cambridge, Dept Chem, Pfizer Inst Pharmaceut Mat Sci, Cambridge CB2 1EW, England

[2] Cambridge Crystallog Data Ctr, Cambridge CB2 1EZ, England

来源：

CHEMICAL COMMUNICATIONS | 2006年 / 01期

关键词：

D O I：

10.1039/b512626f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Neat grinding and solvent-drop grinding methods are found to be effective screening tools for indicating the potential for crystalline salt formation involving a given acid-base pair, as demonstrated with two model pharmaceuticals.

引用

页码：51 / 53

页数：3

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