Synthesis of all possible regioisomers of myo-inositol pentakisphosphate

被引：21

作者：

Chung, SK

Chang, YT

机构：

[1] Department of Chemistry, Pohang University of Science and Technology

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1996年 / 6卷 / 17期

关键词：

D O I：

10.1016/0960-894X(96)00371-X

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Synthesis of all possible 4 regioisomers of IP5, naturally occurring metabolites of IP3, and IP4, was accomplished from myo-inositol via its monobenzoate derivatives (IBz(1)) as the key intermediates; base-catalyzed isomerization of readily available IBz(1) derivatives, followed by suitable separation procedures efficiently provided the requisite regioisomers of IBz(1). Copyright (C) 1996 Elsevier Science Ltd

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页码：2039 / 2042

页数：4

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