From words to literature in structural proteomics

被引：344

作者：

Sali, A ^{[1
]}

Glaeser, R

Earnest, T

Baumeister, W

机构：

[1] Univ Calif San Francisco, Dept Biopharmaceut Sci, San Francisco, CA 94143 USA

[2] Univ Calif San Francisco, Dept Pharmaceut Chem, San Francisco, CA 94143 USA

[3] Univ Calif San Francisco, Calif Inst Quantitat Biomed Res, San Francisco, CA 94143 USA

[4] Univ Calif Berkeley, Dept Mol & Cell Biol, Stanley Donner ASU, Berkeley, CA 94720 USA

[5] Univ Calif Berkeley, Lawrence Berkeley Lab, Phys Biosci Div, Berkeley Ctr Struct Biol, Berkeley, CA 94720 USA

[6] Max Planck Inst Biochem, Dept Biol Struct, D-82152 Martinsried, Germany

来源：

NATURE | 2003年 / 422卷 / 6928期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1038/nature01513

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Technical advances on several frontiers have expanded the applicability of existing methods in structural biology and helped close the resolution gaps between them. As a result, we are now poised to integrate structural information gathered at multiple levels of the biological hierarchy - from atoms to cells - into a common framework. The goal is a comprehensive description of the multitude of interactions between molecular entities, which in turn is a prerequisite for the discovery of general structural principles that underlie all cellular processes.

引用

页码：216 / 225

页数：10

共 100 条

[11] Electron tomography of molecules and cells [J].

Baumeister, W ;

Grimm, R ;

Walz, J .

TRENDS IN CELL BIOLOGY, 1999, 9 (02) :81-85

[12] Electron tomography: towards visualizing the molecular organization of the cytoplasm [J].

Baumeister, W .

CURRENT OPINION IN STRUCTURAL BIOLOGY, 2002, 12 (05) :679-684

[13] Macromolecular electron microscopy in the era of structural genomics [J].

Baumeister, W ;

Steven, AC .

TRENDS IN BIOCHEMICAL SCIENCES, 2000, 25 (12) :624-631

[14] Toward detecting and identifying macromolecules in a cellular context:: Template matching applied to electron tomograms [J].

Böhm, J ;

Frangakis, AS ;

Hegerl, R ;

Nickell, S ;

Typke, D ;

Baumeister, W .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (26) :14245-14250

[15] De novo prediction of three-dimensional structures for major protein families [J].

Bonneau, R ;

Strauss, CEM ;

Rohl, CA ;

Chivian, D ;

Bradley, P ;

Malmström, L ;

Robertson, T ;

Baker, D .

JOURNAL OF MOLECULAR BIOLOGY, 2002, 322 (01) :65-78

[16] Ab initio protein structure prediction: Progress and prospects [J].

Bonneau, R ;

Baker, D .

ANNUAL REVIEW OF BIOPHYSICS AND BIOMOLECULAR STRUCTURE, 2001, 30 :173-189

[17] Determination of the fold of the core protein of hepatitis B virus ky electron cryomicroscopy [J].

Bottcher, B ;

Wynne, SA ;

Crowther, RA .

NATURE, 1997, 386 (6620) :88-91

[18] Structural genomics: beyond the Human Genome Project [J].

Burley, SK ;

Almo, SC ;

Bonanno, JB ;

Capel, M ;

Chance, MR ;

Gaasterland, T ;

Lin, DW ;

Sali, A ;

Studier, FW ;

Swaminathan, S .

NATURE GENETICS, 1999, 23 (02) :151-157

[19] Leginon: An automated system for acquisition of images from vitreous ice specimens [J].

Carragher, B ;

Kisseberth, N ;

Kriegman, D ;

Milligan, RA ;

Potter, CS ;

Pulokas, J ;

Reilein, A .

JOURNAL OF STRUCTURAL BIOLOGY, 2000, 132 (01) :33-45

[20] Multi-resolution contour-based fitting of macromolecular structures [J].

Chacón, P ;

Wriggers, W .

JOURNAL OF MOLECULAR BIOLOGY, 2002, 317 (03) :375-384

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