Secoorthosiphols A-C:: three highly oxygenated secoisopimarane-type diterpenes from Orthosiphon stamineus

被引：16

作者：

Awale, S

Tezuka, Y

Shimoji, S

Taira, K

Kadota, S

机构：

[1] Toyama Med & Pharmaceut Univ, Inst Nat Med, Toyama 9300194, Japan

[2] Okinawa Hlth Food Dev Cooperat, Okinawa 9011414, Japan

[3] Univ Ryukyus, Fac Educ, Nishihara, Okinawa 9030129, Japan

来源：

TETRAHEDRON LETTERS | 2002年 / 43卷 / 08期

关键词：

D O I：

10.1016/S0040-4039(02)00037-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Three new highly oxygenated 2,3-secoisopimarane-type diterpenes, named secoorthosiphols A (1). B (2) and C (3). have been isolated as extremely minor constituents from the aerial parts of the Orthosiphon stamineus from Okinawa. A unique unprecedented structural feature of such a ring A opened system in newly isolated Compounds was encountered for the first time in isopimarane-type diterpenes. Secoorthosiphol C (3) represents the first example of a biogenetically unique and unconventional secoisopimarane-type diterpene having, a cyano group. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：1473 / 1475

页数：3

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