A simple procedure for the solid phase synthesis of diketopiperazine and diketomorpholine derivatives

被引：120

作者：

Szardenings, AK

Burkoth, TS

Lu, HH

Tien, DW

Campbell, DA

机构：

来源：

TETRAHEDRON | 1997年 / 53卷 / 19期

关键词：

D O I：

10.1016/S0040-4020(97)00218-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel route for the synthesis of diketopiperazines and diketomorpholines on a solid support is described. Two different approaches are reported for diketopiperazines. The cyclization step involves cyclization with simultaneous cleavage from the resin. (C) 1997 Published by Elsevier Science Ltd.

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页码：6573 / 6593

页数：21

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