Antibody gene therapy: Old wine in a new bottle

被引:5
作者
Chen, LP [1 ]
机构
[1] Mayo Clin, Mayo Grad Sch, Dept Immunol, Rochester, MN 55905 USA
[2] Mayo Clin, Mayo Med Sch, Rochester, MN 55905 USA
关键词
D O I
10.1038/nm0402-333
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Tumor cells engineered to overexpress molecules that activate an immune response have shown therapeutic promise in preventing growth of cancers. In a new study, tumor cells studded with a ligand-mimicking antibody fragment beckon their own destruction. (pages 343–348)
引用
收藏
页码:333 / 334
页数:2
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