Paravalvular Leak After Transcatheter Aortic Valve Replacement The New Achilles' Heel? A Comprehensive Review of the Literature

被引：325

作者：

Genereux, Philippe ^{[1
,2
,3
]}

Head, Stuart J. ^{[4
]}

Hahn, Rebecca ^{[1
,2
]}

Daneault, Benoit ^{[1
,2
]}

Kodali, Susheel ^{[1
,2
]}

Williams, Mathew R. ^{[1
,2
]}

van Mieghem, Nicolas M. ^{[5
]}

Alu, Maria C. ^{[1
]}

Serruys, Patrick W. ^{[5
]}

Kappetein, A. Pieter ^{[4
]}

Leon, Martin B. ^{[1
,2
]}

机构：

[1] Columbia Univ, Med Ctr, New York Presbyterian Hosp, New York, NY 10032 USA

[2] Cardiovasc Res Fdn, New York, NY USA

[3] Hop Sacre Coeur Montreal, Montreal, PQ, Canada

[4] Erasmus Univ, Med Ctr, Dept Cardiothorac Surg, Rotterdam, Netherlands

[5] Erasmus Univ, Dept Cardiol, Med Ctr, Rotterdam, Netherlands

来源：

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY | 2013年 / 61卷 / 11期

关键词：

aortic stenosis; paravalvular leak; TAVI; TAVR; MULTIDETECTOR COMPUTED-TOMOGRAPHY; 3-DIMENSIONAL TRANSESOPHAGEAL ECHOCARDIOGRAPHY; VENA CONTRACTA AREA; CARDIAC-OUTPUT; IMPLANTATION IMPACT; FOLLOW-UP; EAE/ASE RECOMMENDATIONS; DOPPLER DETERMINATION; HEMODYNAMIC OUTCOMES; STANDARDS COMMITTEE;

D O I：

10.1016/j.jacc.2012.08.1039

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Paravalvular leak (PVL) is a frequent complication of transcatheter aortic valve replacement (TAVR) and is seen at a much higher rate after TAVR than after conventional surgical aortic valve replacement. Recent reports indicating that PVL may be correlated with increased late mortality have raised concerns. However, the heterogeneity of methods for assessing and quantifying PVL, and lack of consistency in the timing of such assessments, is a hindrance to understanding its true prevalence, severity, and effect. This literature review is an effort to consolidate current knowledge in this area to better understand the prevalence, progression, and impact of post-TAVR PVL and to help direct future efforts regarding the assessment, prevention, and treatment of this troublesome complication. (J Am Coll Cardiol 2013;61:1125-36) (C) 2013 by the American College of Cardiology Foundation

引用

页码：1125 / 1136

页数：12

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