Microfluidics and photonics for Bio-System-on-a-Chip: A review of advancements in technology towards a microfluidic flow cytometry chip

被引：130

作者：

Godin, Jessica ^{[1
]}

Chen, Chun-Hao ^{[1
]}

Cho, Sung Hwan ^{[1
]}

Qiao, Wen ^{[2
]}

Tsai, Frank ^{[1
]}

Lo, Yu-Hwa ^{[1
]}

机构：

[1] Univ Calif San Diego, Dept Elect & Comp Engn, La Jolla, CA 92093 USA

[2] Zhejiang Univ, State Key Lab, Natl Engn Res Ctr Opt Instrument, Hangzhou, Zhejiang, Peoples R China

来源：

JOURNAL OF BIOPHOTONICS | 2008年 / 1卷 / 05期

关键词：

Biomedical instrumentation and transducers; including micro-electro-mechanical systems (MEMS); cells on a chip; other integrated-optical elements and systems; fabrication techniques; lithography; pattern transfer; flows in micro-electromechanical systems (MEMS) and nanoelectromechanical systems (NEMS); fluorescence;

D O I：

10.1002/jbio.200810018

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Microfluidics and photonics come together to form a field commonly referred to as 'optofluidics'. Flow cytometry provides the field with a technology base from which both microfluidic and photonic components be developed and integrated into a useful device. This article reviews some of the more recent developments to familiarize a reader with the current state of the technologies and also highlights the requirements of the device and how researchers are working to meet these needs A microfluidic flow cytometer prototype employing on-chip lenses for illumination and light collection in conjunction with a microfluidic sample flow system for device miniaturization.

引用

页码：355 / 376

页数：22

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