Cerebellar cortex: Computation by extrasynaptic inhibition?

被引:19
作者
De Schutter, E [1 ]
机构
[1] Univ Instelling Antwerp, Born Bunge Fdn, B-2610 Antwerp, Belgium
关键词
D O I
10.1016/S0960-9822(02)00861-8
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
In the cerebellar cortex, inhibitory inputs to granule cells exhibit prominent tonic and spillover components resulting from the activation of extrasynaptic receptors. A recent study shows how extrasynaptic inhibition affects information flow through cerebellar cortex.
引用
收藏
页码:R363 / R365
页数:3
相关论文
共 20 条
[1]  
ALBUS J S, 1971, Mathematical Biosciences, V10, P25, DOI 10.1016/0025-5564(71)90051-4
[2]   Development of a tonic form of synaptic inhibition in rat cerebellar granule cells resulting from persistent activation of GABA(A) receptors [J].
Brickley, SG ;
CullCandy, SG ;
Farrant, M .
JOURNAL OF PHYSIOLOGY-LONDON, 1996, 497 (03) :753-759
[3]   Adaptive regulation of neuronal excitability by a voltage-independent potassium conductance [J].
Brickley, SG ;
Revilla, V ;
Cull-Candy, SG ;
Wisden, W ;
Farrant, M .
NATURE, 2001, 409 (6816) :88-92
[4]   Generating diversity at GABAergic synapses [J].
Cherubini, E ;
Conti, F .
TRENDS IN NEUROSCIENCES, 2001, 24 (03) :155-162
[5]   Evidence for NMDA and mGlu receptor-dependent long-term potentiation of mossy fiber-granule cell transmission in rat cerebellum [J].
D'Angelo, E ;
Rossi, P ;
Armano, S ;
Taglietti, V .
JOURNAL OF NEUROPHYSIOLOGY, 1999, 81 (01) :277-287
[6]  
De Schutter E, 2000, PROG BRAIN RES, V124, P81
[7]   Submillisecond kinetics and low efficacy of parallel fibre Golgi cell synaptic currents in the rat cerebellum [J].
Dieudonné, S .
JOURNAL OF PHYSIOLOGY-LONDON, 1998, 510 (03) :845-866
[8]   Tonic and spillover inhibition of granule cells control information flow through cerebellar cortex [J].
Hamann, M ;
Rossi, DJ ;
Attwell, D .
NEURON, 2002, 33 (04) :625-633
[9]   Shunting inhibition does not have a divisive effect on firing rates [J].
Holt, GR ;
Koch, C .
NEURAL COMPUTATION, 1997, 9 (05) :1001-1013
[10]   Synchronization of Golgi and granule cell firing in a detailed network model of the cerebellar granule cell layer [J].
Maex, R ;
De Schutter, E .
JOURNAL OF NEUROPHYSIOLOGY, 1998, 80 (05) :2521-2537