Ampicillin trihydrate from synchrotron powder diffraction data

被引：19

作者：

Burley, JC

van de Streek, J

Stephens, PW

机构：

[1] Univ Cambridge, Chem Lab, Cambridge CB2 1EW, England

[2] Cambridge Crystallog Data Ctr, Cambridge CB2 1EZ, England

[3] SUNY Stony Brook, Dept Phys & Astron, Stony Brook, NY 11794 USA

来源：

ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS | 2006年 / 62卷

关键词：

D O I：

10.1107/S1600536806001371

中图分类号：

O7 [晶体学];

学科分类号：

0702 ; 070205 ; 0703 ; 080501 ;

摘要：

The crystal structure of ampicillin trihydrate {systematic name: 6-[D(-)-alpha-aminophenylacetamido]penicillanic acid trihydrate}, C16H19N3O4S center dot 3H(2)O, a broad-spectrum beta-lactam antibiotic of the aminopenicillin type, has been determined from synchrotron X-ray powder diffraction data. The three water molecules form an infinite hydrogen-bonded chain through the crystal structure, with hydrogen bonds to the NH3+, COO-, C=O and NH groups of the ampicillin molecules.

引用

页码：O797 / O799

页数：3