Direct C-arylation of β-enamino esters and ketones with arynes

被引：94

作者：

Ramtohul, Yeeman K. ^{[1
]}

Chartrand, Anik ^{[1
]}

机构：

[1] Merck Frosst Canada Inc, Merck Frosst Ctr Therapeut Res, Dept Med Chem, Kirkland, PQ H9H 3L1, Canada

来源：

ORGANIC LETTERS | 2007年 / 9卷 / 06期

关键词：

D O I：

10.1021/ol063057k

中图分类号：

O62 [有机化学];

学科分类号：

070303 [有机化学]; 081704 [应用化学];

摘要：

An efficient, mild, and general method for the C-arylation beta-enamino esters and ketones with arynes has been developed. This methodology provides a facile and direct access to a variety of substituted aromatic beta-enamino compounds in moderate to excellent yield.

引用

页码：1029 / 1032

页数：4

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