Confocal fluorescence imaging of DNA-functionalized carbon nanotubes

被引:137
作者
Hazani, M
Naaman, R [1 ]
Hennrich, F
Kappes, MM
机构
[1] Weizmann Inst Sci, Dept Phys Chem, IL-76100 Rehovot, Israel
[2] Forschungszentrum Karlsruhe, Inst Nanotechnol, D-76021 Karlsruhe, Germany
关键词
D O I
10.1021/nl025874t
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Single-walled carbon nanotubes (SWNT) were covalently modified with DNA via carbodlimide-assisted amidation, yielding a highly watersoluble adduct. The specific and nonspecific interactions between DNA and SWNTs were examined by UV-vis spectroscopy and confocal fluorescence microscopy. Fluorescence imaging of individual bundles shows that the SWNT-DNA adducts hybridize selectively with complementary strands with minimal nonspecific interactions with noncomplementary sequences.
引用
收藏
页码:153 / 155
页数:3
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