A tomato cysteine protease required for Cf-2-dependent disease resistance and suppression of autonecrosis

被引：322

作者：

Krüger, J

Thomas, CM

Golstein, C

Dixon, MS

Smoker, M

Tang, SK

Mulder, L

Jones, JDG ^{[1
]}

机构：

[1] John Innes Ctr Plant Sci Res, Sainsbury Lab, Norwich NR4 7UH, Norfolk, England

[2] Univ E Anglia, Sch Biol Sci, Norwich NR4 7TJ, Norfolk, England

[3] Indiana Univ, Dept Biol, Bloomington, IN 47405 USA

[4] Univ Southampton, Sch Biol Sci, Southampton SO16 7PX, Hants, England

[5] Univ N Carolina, Dept Biol, Chapel Hill, NC 27599 USA

来源：

SCIENCE | 2002年 / 296卷 / 5568期

关键词：

D O I：

10.1126/science.1069288

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Little is known of how plant disease resistance (R) proteins recognize pathogens and activate plant defenses. Rcr3 is specifically required for the function of Cf-2, a Lycopersicon pimpinellifolium gene bred into cultivated tomato (Lycopersicon esculentum) for resistance to Cladosporium fulvum. Rcr3 encodes a secreted papain-like cysteine endoprotease. Genetic analysis shows Rcr3 is allelic to the L. pimpinellifolium Ne gene, which suppresses the Cf-2-dependent autonecrosis conditioned by its L. esculentum allele, ne (necrosis). Rcr3 alleles from these two species encode proteins that differ by only seven amino acids, Possible roles of Rcr3 in Cf-2-dependent defense and autonecrosis are discussed.

引用

页码：744 / 747

页数：4

共 21 条

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