Biomolecular motors

被引:38
作者
Hess, Henry [1 ]
Bachand, George D. [2 ]
机构
[1] Univ Florida, Dept Mat Sci & Engn, Gainesville, FL 32611 USA
[2] Sandia Natl Labs, Albuquerque, NM 87185 USA
关键词
D O I
10.1016/S1369-7021(05)71286-4
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
The efficient conversion of chemical energy into mechanical work by specialized biological nanomachines enables a wide range of functions in nature, ranging from intracellular transport to large-scale actuation by muscles. Through suitable interfaces, these motor proteins can be employed in synthetic nanodevices with applications in biosensing, self-assembly, and molecular-scale actuation. Here, we give a brief introduction to molecular motors, with an emphasis on motor proteins, describe the challenges in interfacing these bionanomachines with an artificial environment, and provide examples of emerging applications.
引用
收藏
页码:22 / 29
页数:8
相关论文
共 105 条
[71]   In vitro sliding of actin filaments labelled with single quantum dots [J].
Månsson, A ;
Sundberg, M ;
Balaz, M ;
Bunk, R ;
Nicholls, IA ;
Omling, P ;
Tågerud, S ;
Montelius, L .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2004, 314 (02) :529-534
[72]   Molecules, muscles, and machines: Universal performance characteristics of motors [J].
Marden, JH ;
Allen, LR .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2002, 99 (07) :4161-4166
[73]   A novel biosensor for mercuric ions based on motor proteins [J].
Martinez-Neira, R ;
Kekic, M ;
Nicolau, D ;
dos Remedios, CG .
BIOSENSORS & BIOELECTRONICS, 2005, 20 (07) :1428-1432
[74]   All-electrical switching and control mechanism for actomyosin-powered nanoactuators [J].
Mihajlovic, G ;
Brunet, NM ;
Trbovic, J ;
Xiong, P ;
von Molnár, S ;
Chase, PB .
APPLIED PHYSICS LETTERS, 2004, 85 (06) :1060-1062
[75]   Lithographically patterned channels spatially segregate kinesin motor activity and effectively guide microtubule movements [J].
Moorjani, SG ;
Jia, L ;
Jackson, TN ;
Hancock, WO .
NANO LETTERS, 2003, 3 (05) :633-637
[76]   Actin motion on microlithographically functionalized myosin surfaces and tracks [J].
Nicolau, DV ;
Suzuki, H ;
Mashiko, S ;
Taguchi, T ;
Yoshikawa, S .
BIOPHYSICAL JOURNAL, 1999, 77 (02) :1126-1134
[77]   Dispersion in active transport by kinesin-powered molecular shuttles [J].
Nitta, T ;
Hess, H .
NANO LETTERS, 2005, 5 (07) :1337-1342
[78]   A tightly regulated molecular motor based upon T7 RNA polymerase [J].
Pomerantz, RT ;
Ramjit, R ;
Gueroui, Z ;
Place, C ;
Anikin, M ;
Leuba, S ;
Zlatanova, J ;
McAllister, WT .
NANO LETTERS, 2005, 5 (09) :1698-1703
[79]   Bionanomechanical systems [J].
Schmidt, JJ ;
Montemagno, CD .
ANNUAL REVIEW OF MATERIALS RESEARCH, 2004, 34 :315-337
[80]   Force tolerances of hybrid nanodevices [J].
Schmidt, JJ ;
Jiang, XQ ;
Montemagno, CD .
NANO LETTERS, 2002, 2 (11) :1229-1233