共 12 条
Polyenylpyrroles and polyenylfurans from an Australian isolate of the soil ascomycete Gymnoascus reessii
被引:63
作者:
Clark, BR
[1
]
Capon, RJ
Lacey, E
Tennant, S
Gill, JH
机构:
[1] Univ Queensland, Inst Mol Biosci, Brisbane, Qld 4072, Australia
[2] Microbial Screening Technol Pty Ltd, Smithfield, NSW 2164, Australia
关键词:
D O I:
10.1021/ol052880y
中图分类号:
O62 [有机化学];
学科分类号:
070303 ;
081704 ;
摘要:
An Australian isolate of the soil ascomycete Gymnoascus reessii yielded a series of cytotoxic metabolites, including the known polyenylpyrroles rumbrin (1) and auxarconjugatin A (2), and the new rumbrin stereoisomer 12E-isorumbrin (3), as well as an unprecedented class of polyenylfurans exemplified by gymnoconjugatins A (4) and B (5). Structures were assigned with detailed spectroscopic analysis.
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页码:701 / 704
页数:4
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