The phosphine-catalyzed alkyne to 1,3-diene isomerization reaction

被引：103

作者：

Kwong, Cathy Kar-Wing ^{[1
]}

Fu, Michael Yunyi ^{[1
]}

Lam, Cynthia Sze-Lok ^{[1
]}

Toy, Patrick H. ^{[1
]}

机构：

[1] Univ Hong Kong, Dept Chem, Hong Kong, Hong Kong, Peoples R China

来源：

SYNTHESIS-STUTTGART | 2008年 / 15期

关键词：

organocatalysis; isotnerization reactions; phosphines; alkynes; 1,3-dienes;

D O I：

10.1055/s-2008-1067173

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The alkyne to 1,3-diene isomerization reaction is a process in which a nucleophilic phosphine catalyst promotes the rearrangement of an electron-withdrawing group activated alkyne to the corresponding conjugated diene. The origin, mechanism, development, and application of this organocatalytic and stereoselective reaction in the synthesis of complex organic molecules are reviewed. 1 Introduction 2 The Reaction 2.1 Background 2.2 Mechanism 2.3 Development 2.4 Synthetic Applications 3 Conclusions

引用

页码：2307 / 2317

页数：11

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