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Ascorbic acid: much more than just an antioxidant

被引：777
作者：
Arrigoni, O [1 ]
De Tullio, MC [1 ]
机构：
[1] Univ Bari, Dipartimento BIol & Patol Vegetale, I-70125 Bari, Italy
来源：
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS | 2002年 / 1569卷 / 1-3期
关键词：
ascorbic acid; dehydroascorbic acid; oxoglutarate-dependent dioxygenase;
D O I：
10.1016/S0304-4165(01)00235-5
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Vitamin C (ascorbic acid (AA)) is very popular for its antioxidant properties. Consequently, many other important aspects of this multifaceted molecule are often underestimated or even ignored. In the present paper, we have tried to bring to the foreground some of these aspects, including the peculiarities of the AA biosynthetic pathway in different organisms, the remarkable function of AA as a co-substrate of many important dioxygenases, the role of AA-regenerating enzymes and the known pathways of AA catabolism, as well as the intriguing function of AA in gene expression. (C) 2002 Elsevier Science B.V. All rights reserved.
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页码：1 / 9
页数：9
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