PINK1-and Parkin-mediated mitophagy at a glance

被引:465
作者
Jin, Seok Min [1 ]
Youle, Richard J. [1 ]
机构
[1] NINDS, Biochem Sect, Surg Neurol Branch, NIH, Bethesda, MD 20892 USA
关键词
MITOCHONDRIAL-DNA DELETIONS; SUBSTANTIA-NIGRA NEURONS; PROTEIN-DEGRADATION; PINK1/PARKIN-MEDIATED MITOPHAGY; RETICULOCYTE MATURATION; OXIDATIVE STRESS; KINASE PINK1; DISEASE; AUTOPHAGY; MUTATIONS;
D O I
10.1242/jcs.093849
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
[No abstract available]
引用
收藏
页码:795 / 799
页数:5
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共 60 条
  • [51] Hereditary early-onset Parkinson's disease caused by mutations in PINK1
    Valente, EM
    Abou-Sleiman, PM
    Caputo, V
    Muqit, MMK
    Harvey, K
    Gispert, S
    Ali, Z
    Del Turco, D
    Bentivoglio, AR
    Healy, DG
    Albanese, A
    Nussbaum, R
    González-Maldonaldo, R
    Deller, T
    Salvi, S
    Cortelli, P
    Gilks, WP
    Latchman, DS
    Harvey, RJ
    Dallapiccola, B
    Auburger, G
    Wood, NW
    [J]. SCIENCE, 2004, 304 (5674) : 1158 - 1160
  • [52] PINK1-dependent recruitment of Parkin to mitochondria in mitophagy
    Vives-Bauza, Cristofol
    Zhou, Chun
    Huang, Yong
    Cui, Mei
    de Vries, Rosa L. A.
    Kim, Jiho
    May, Jessica
    Tocilescu, Maja Aleksandra
    Liu, Wencheng
    Ko, Han Seok
    Magrane, Jordi
    Moore, Darren J.
    Dawson, Valina L.
    Grailhe, Regis
    Dawson, Ted M.
    Li, Chenjian
    Tieu, Kim
    Przedborski, Serge
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2010, 107 (01) : 378 - 383
  • [53] Rhomboid-7 and HtrA2/Omi act in a common pathway with the Parkinson's disease factors Pink1 and Parkin
    Whitworth, Alexander J.
    Lee, Jeffrey R.
    Ho, Venus M-W.
    Flick, Robert
    Chowdhury, Ruhena
    McQuibban, G. Angus
    [J]. DISEASE MODELS & MECHANISMS, 2008, 1 (2-3) : 168 - 174
  • [54] Mitochondrial dysfunction and oxidative stress mediate the physiological impairment induced by the disruption of autophagy
    Wu, J. Julie
    Quijano, Celia
    Chen, Edmund
    Liu, Hongjun
    Cao, Liu
    Fergusson, Maria M.
    Rovira, Ilsa I.
    Gutkind, Sarah
    Daniels, Mathew P.
    Komatsu, Masaaki
    Finkel, Toren
    [J]. AGING-US, 2009, 1 (04): : 425 - 437
  • [55] Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation
    Xiong, Hui
    Wang, Danling
    Chen, Linan
    Choo, Yeun Su
    Ma, Hong
    Tang, Chengyuan
    Xia, Kun
    Jiang, Wei
    Ronai, Ze'ev
    Zhuang, Xiaoxi
    Zhang, Zhuohua
    [J]. JOURNAL OF CLINICAL INVESTIGATION, 2009, 119 (03) : 650 - 660
  • [56] The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol
    Ye, YH
    Meyer, HH
    Rapoport, TA
    [J]. NATURE, 2001, 414 (6864) : 652 - 656
  • [57] Parkin Mediates Proteasome-dependent Protein Degradation and Rupture of the Outer Mitochondrial Membrane
    Yoshii, Saori R.
    Kishi, Chieko
    Ishihara, Naotada
    Mizushima, Noboru
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2011, 286 (22) : 19630 - 19640
  • [58] Mitochondrial clearance is regulated by Atg7-dependent and -independent mechanisms during reticulocyte maturation
    Zhang, Ji
    Randall, Mindy S.
    Loyd, Melanie R.
    Dorsey, Frank C.
    Kundu, Mondira
    Cleveland, John L.
    Ney, Paul A.
    [J]. BLOOD, 2009, 114 (01) : 157 - 164
  • [59] Adipose-specific deletion of autophagy-related gene 7 (atg7) in mice reveals a role in adipogenesis
    Zhang, Yong
    Goldman, Scott
    Baerga, Rebecca
    Zhao, Yun
    Komatsu, Masaaki
    Jin, Shengkan
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2009, 106 (47) : 19860 - 19865
  • [60] Drosophila Parkin requires PINK1 for mitochondrial translocation and ubiquitinates Mitofusin
    Ziviani, Elena
    Tao, Ran N.
    Whitworth, Alexander J.
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2010, 107 (11) : 5018 - 5023