Promoter polymorphism rs3087456 in the MHC class II transactivator gene is not associated with susceptibility for selected autoimmune diseases in German patient groups

被引：34

作者：

Akkad, DA

Jagiello, P

Szyld, P

Goedde, R

Wieczorek, S

Gross, WL

Epplen, JT ^{[1
]}

机构：

[1] Ruhr Univ Bochum, Dept Human Genet, D-44801 Bochum, Germany

[2] Univ Hosp Luebeck, Dept Rheumatol, Lubeck, Germany

[3] Rheumaklin Bad Bramstedt, D-24576 Bad Bramstedt, Germany

来源：

INTERNATIONAL JOURNAL OF IMMUNOGENETICS | 2006年 / 33卷 / 01期

关键词：

D O I：

10.1111/j.1744-313X.2006.00568.x

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

We analysed whether the single nucleotide polymorphism (SNP) rs3087456 in the promoter of the MHC class II transactivator (MHC2TA) gene is associated with manifestation of rheumatoid arthritis, multiple sclerosis, narcolepsy and Wegener granulomatosis. The recently reported association in a northern population of the MHC2TA variation with these autoimmune diseases is not evident in the German population.

引用

页码：59 / 61

页数：3

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