Bifunctional asymmetric catalysis:: A tandem nucleophile/Lewis acid promoted synthesis of β-lactams

被引：94

作者：

France, S ^{[1
]}

Wack, H ^{[1
]}

Hafez, AM ^{[1
]}

Taggi, AE ^{[1
]}

Witsil, DR ^{[1
]}

Lectka, T ^{[1
]}

机构：

[1] Johns Hopkins Univ, Dept Chem, Baltimore, MD 21218 USA

来源：

ORGANIC LETTERS | 2002年 / 4卷 / 09期

关键词：

D O I：

10.1021/ol025805l

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

We describe a superior procedure for the catalytic, asymmetric synthesis of beta-lactams using a bifunctional catalyst system consisting of a chiral nucleophile and an achiral Lewis acid.

引用

页码：1603 / 1605

页数：3

共 16 条

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