Prostate Carcinoma: Diffusion-weighted Imaging as Potential Alternative to Conventional MR and 11C-Choline PET/CT for Detection of Bone Metastases

被引：86

作者：

Luboldt, Wolfgang ^{[1
,2
]}

Kuefer, Rainer ^{[3
]}

Blumstein, Norbert ^{[4
]}

Toussaint, Todd L. ^{[1
]}

Kluge, Alexander ^{[1
]}

Seemann, Marcus D. ^{[1
]}

Luboldt, Hans-Joachim ^{[5
]}

机构：

[1] Multiorgan Screening Fdn, Frankfurt, Germany

[2] Univ Hosp Frankfurt, Dept Radiol, D-60590 Frankfurt, Germany

[3] Univ Hosp Ulm, Clin & Policlin Urol, Ulm, Germany

[4] Univ Hosp Ulm, Dept Nucl Med, Ulm, Germany

[5] Univ Hosp Essen, Clin & Policlin Urol, Essen, Germany

来源：

RADIOLOGY | 2008年 / 249卷 / 03期

关键词：

D O I：

10.1148/radiol.2492080038

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

In a technical development study approved by the institutional ethics committee, the feasibility of fast diffusion-weighted imaging as a replacement for conventional magnetic resonance (MR) imaging sequences (short inversion time inversion recovery [STIR] and T1-weighted spin echo [SE]) and positron emission tomography ( PET)/computed tomography (CT) in the detection of skeletal metastases from prostate cancer was evaluated. MR imaging and carbon 11 ((11)C) choline PET/CT data from 11 consecutive prostate cancer patients with bone metastases were analyzed. Diffusion-weighted imaging appears to be equal, if not superior, to STIR and T1-weighted SE sequences and equally as effective as (11)C-choline PET/CT in detection of bone metastases in these patients. Diffusion-weighted imaging should be considered for further evaluation and comparisons with PET/CT for comprehensive whole- body staging and restaging in prostate and other cancers. (c) RSNA, 2008

引用

页码：1017 / 1025

页数：9

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