Emerging extended-spectrum β-lactamases in Proteus mirabilis

被引：80

作者：

Pagani, L

Migliavacca, R

Pallecchi, L

Matti, C

Giacobone, E

Amicosante, G

Romero, E

Rossolini, GM

机构：

[1] Univ Pavia, Sez Microbiol, Dipartimento Sci Morfol Eidol & Clin, I-27100 Pavia, Italy

[2] IRCCS S Matteo, Serv Anal Microbiol, I-27100 Pavia, Italy

[3] Univ Siena, Sez Microbiol, Dipartimento Biol Mol, I-53100 Siena, Italy

[4] Univ Aquila, Dipartimento Sci & Technol Biomed, I-67100 Laquila, Italy

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2002年 / 40卷 / 04期

关键词：

D O I：

10.1128/JCM.40.4.1549-1552.2002

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

beta-Lactamase production was detected in 147 (52%) of 282 consecutive nonduplicate Proteus mirabilis isolates obtained over a 1-year period from the S. Matteo Hospital of Pavia (northern Italy). Seventy isolates (48% of the beta-lactamase producers) were found to produce extended-spectrum beta-lactamases (ESBLs), identified as PER-1 (first report in this species) and TEM-52 in 52 and 18 isolates, respectively. Analysis of clonal diversity of the ESBL producers suggested different spreading patterns for the two ESBL determinants.

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页码：1549 / 1552

页数：4

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