Changes in the concentration and composition of plasma lipoproteins during the acute phase response

被引：110

作者：

Carpentier, YA ^{[1
]}

Scruel, O ^{[1
]}

机构：

[1] Free Univ Brussels, L Deloyers Lab Expt Surg, B-1070 Brussels, Belgium

来源：

CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE | 2002年 / 5卷 / 02期

关键词：

D O I：

10.1097/00075197-200203000-00006

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The acute phase reactions, associated with injury, inflammation, or sepsis, markedly affect the concentration and composition of plasma lipids and lipoproteins. Hepatic production of triglycerides and very low density lipoprotein formation are increased, but do not necessarily result in high plasma triglyceride levels. In contrast, all conditions lower plasma cholesterol by decreasing its content in both low-density and high-density lipoproteins. In addition, substantial changes in protein and lipid composition of lipoproteins are observed that may redefine the function of these particles, but also increase their atherogenic and inflammatory properties. (C) 2002 Lippincott Williams Wilkins.

引用

页码：153 / 158

页数：6

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