Fas-ligand - Iron fist or Achilles' heel?

被引：16

作者：

Hohlbaum, AM ^{[1
]}

Saff, RR ^{[1
]}

Marshak-Rothstein, A ^{[1
]}

机构：

[1] Boston Univ, Sch Med, Dept Microbiol, Boston, MA 02118 USA

来源：

CLINICAL IMMUNOLOGY | 2002年 / 103卷 / 01期

关键词：

Fas-ligand; monocytes/macrophages; apoptosis; chemokines; neutrophils; inflammation; transplantation; proliferation; signaling;

D O I：

10.1006/clim.2001.5165

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Experimental and physiological expression of the pro-apoptotic molecule Fas-ligand can induce inflammation under certain conditions. Discussed here are the experimental situations, possible mechanisms, and pathways that mediate this response. (C) 2002 Elsevier Science (USA).

引用

页码：1 / 6

页数：6

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