An efficient synthesis of pyrrolo[2,1-c][1,4]benzodiazepine antibiotics via reductive cyclization

被引：24

作者：

Kamal, A

Reddy, BSN

Reddy, BSP

机构：

[1] Division of Organic Chemistry, Indian Inst. of Chemical Technology

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1997年 / 7卷 / 14期

关键词：

D O I：

10.1016/S0960-894X(97)00314-4

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A new and convenient one-pot synthesis of pyrrolo[2,1-c][1,4]benzodiazepine (PBD) ring system has been achieved by a reductive cyclization employing N,N-dimethylhydrazine and FeCl3.6H(2)O in good yields. (C) 1997 Elsevier Science Ltd.

引用

页码：1825 / 1828

页数：4