Phosphinooxazolines - A new class of versatile, modular P,N-ligands for asymmetric catalysis

被引：1222

作者：

Helmchen, G

Pfaltz, A

机构：

[1] Univ Heidelberg, Inst Organ Chem, D-69120 Heidelberg, Germany

[2] Univ Basel, Dept Chem, CH-4056 Basel, Switzerland

来源：

ACCOUNTS OF CHEMICAL RESEARCH | 2000年 / 33卷 / 06期

关键词：

D O I：

10.1021/ar9900865

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Chiral phosphinooxazolines (PHOX ligands), which coordinate to a metal center with a N- and a P-atom, allow effective enantio-control in a variety of metal-catalyzed reactions. They are readily synthesized, and because of their modular structure, the steric and electronic properties can be tailored for a specific application by variation of the oxazoline ring, the backbone, and the phosphine moiety.

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页码：336 / 345

页数：10

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