DNA repair: RAD alert

被引:24
作者
Ivanov, EL
Haber, JE
机构
[1] BRANDEIS UNIV,ROSENSTIEL BASIC MED SCI RES CTR,WALTHAM,MA 02254
[2] BRANDEIS UNIV,DEPT BIOL,WALTHAM,MA 02254
关键词
D O I
10.1016/S0960-9822(06)00246-6
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Mammalian homologues of two important yeast genes involved in DNA double-strand break repair and recombination, RAD51 and RAD54, have been isolated, Knock-out mutations of the genes in mice reveal both reassuring similarities to, and surprising differences from, the analogous mutant phenotypes in yeast.
引用
收藏
页码:R492 / R495
页数:4
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