Enantioselective acyclic stereoselection under catalyst control .2. asymmetric synthesis of syn- and anti-1,3-diols incorporating an acetate equivalent by the chiral oxazaborolidinone-catalyzed aldol reaction

被引：28

作者：

Kiyooka, S ^{[1
]}

Yamaguchi, T ^{[1
]}

Maeda, H ^{[1
]}

Kira, H ^{[1
]}

Hena, MA ^{[1
]}

Horiike, M ^{[1
]}

机构：

[1] KOCHI UNIV, DEPT BIOSOURCES SCI, NANKO KU, KOCHI 780, JAPAN

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 20期

关键词：

D O I：

10.1016/S0040-4039(97)00701-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The chiral oxazaborolidinone-catalysed aldol reaction of a silyl ketene acetal involving a dithiolane moiety with beta-silyloxy aldehyde resulted in the production of syn- and anti-1,3-diols with complete stereoselection by the choice of the stereochemistry of the catalyst. This reaction is an elegant example of enantioselective acyclic stereoselection under catalyst control. (C) 1997 Elsevier Science Ltd.

引用

页码：3553 / 3556

页数：4

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