Potentiometric titrations in a poly(dimethylsiloxane)-based microfluidic device

被引：22

作者：

Ferrigno, R ^{[1
]}

Lee, JN ^{[1
]}

Jiang, XY ^{[1
]}

Whitesides, GM ^{[1
]}

机构：

[1] Harvard Univ, Dept Chem & Biol Chem, Cambridge, MA 02138 USA

来源：

ANALYTICAL CHEMISTRY | 2004年 / 76卷 / 08期

关键词：

D O I：

10.1021/ac035281i

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

This paper describes a microfluidic device, fabricated in poly(dimethylsiloxane), that is used for potentiometric titrations. This system generates step gradients of redox potentials in a series of microchannels. These potentials are probed by microelectrodes that are integrated into the chip; the measured potentials were used to produce a titration curve from which the end point of a reaction was measured.

引用

页码：2273 / 2280

页数：8

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