Aryl halide tolerated electrophilic amination of arylboronic acids with N-chloroamides catalyzed by CuCl at room temperature

被引：118

作者：

He, Chuan ^{[1
]}

Chen, Chong ^{[1
]}

Cheng, Jin ^{[1
]}

Liu, Chao ^{[1
]}

Liu, Wei ^{[1
]}

Li, Qiang ^{[1
]}

Lei, Aiwen ^{[1
]}

机构：

[1] Wuhan Univ, Coll Chem & Mol Sci, Wuhan 430072, Hubei, Peoples R China

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2008年 / 47卷 / 34期

基金：

中国国家自然科学基金;

关键词：

amides; amination; copper; cross-coupling; homogeneous catalysis;

D O I：

10.1002/anie.200801427

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Chemical Equation Presented) N-Cl is no competition: Aryl halides were tolerated in an efficient ligandless CuCl-catalyzed electrophilic amination reaction of arylboronic acids with N-chloroamides (see scheme; Ac=acetoxy). This coupling proceeded smoothly at ambient temperature, and products were obtained with good to excellent yields. © 2008 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：6414 / 6417

页数：4

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