Nickel-catalyzed electrophilic amination of organozinc halides

被引：64

作者：

Berman, AM ^{[1
]}

Johnson, JS ^{[1
]}

机构：

[1] Univ N Carolina, Dept Chem, Chapel Hill, NC 27599 USA

来源：

SYNLETT | 2005年 / 11期

关键词：

amination; organometallic reagents; nickel; catalysis; umpolung;

D O I：

10.1055/s-2005-871567

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The nickel-catalyzed electrophilic amination of organozinc halides with O-benzoyl N,N-dialkyl hydroxylamines allows for the preparation of a variety of aryl and alkyl tertiary amines in good yield. The reaction is noteworthy for the mild reaction conditions employed (room temperature) and the ease of product purification (acid/base extractive work up).

引用

收藏

页码：1799 / 1801

页数：3

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