Measuring tobacco smoke exposure: quantifying nicotine/cotinine concentration in biological samples by colorimetry, chromatography and immunoassay methods

被引：112

作者：

Dhar, P ^{[1
]}

机构：

[1] SUNY Albany, Dept Chem, New Paltz, NY 12561 USA

来源：

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS | 2004年 / 35卷 / 01期

关键词：

nicotine; cotinine; cortisol;

D O I：

10.1016/j.jpba.2004.01.009

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Procedures to assess tobacco smoke exposure are reviewed and biomarkers used for determining the smoking status of an individual are compared. Methods used to extract these biomarkers from saliva, urine, and blood and the advantages and disadvantages of the assays are discussed. Finally, the procedures used to measure the levels of cortisol, a stress hormone speculated to be linked to nicotine metabolism, are discussed. (C) 2004 Elsevier B.V. All rights reserved.

引用

页码：155 / 168

页数：14

共 186 条

[21] STEREOSPECIFIC MONOCLONAL-ANTIBODIES TO NICOTINE AND COTININE AND THEIR USE IN ENZYME-LINKED IMMUNOSORBENT ASSAYS [J].